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Fatigue Fix

A rejuvenating bio-active Serum to revitalise tired, dry skin and restore radiance.

Annee de Mamiel

Founded by acclaimed skin health specialist Annee de Mamiel, de Mamiel is a collection of natural formulas activated by science and designed to treat the impact of stress on the skin. Every product is made by hand in the lab of de Mamiel in the British countryside and is powered by Annee’s extensive expertise, clinical practice and skin health know-how.

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Annee de Mamiel

New: Fatigue Fix

Fatigue Fix targets stress-induced dullness and dehydration which occurs when long-term elevated cortisol slows down cellular turnover and disrupts the protective skin barrier which in turn reduces the skin’s ability to retain moisture.


85% of testers said their skin appears revitalised.


84% of testers said their skin appears rejuvenated.


86% of testers said their skin appears brighter.

New: Fatigue Fix

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